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  1. ..., were reportedly diagnosed with type 2 diabetes mellitus in their sixth decade. The proband’s father had a normal HbA1c on therapy with metformin band 21.3 years (no treatment) 26.4 years (metformin 1.5 g/day) cose (mmol/l) Insulin (pmol/l) Glucose (mmol/l) Insulin (pmol/l) 5.4 201 – – 5.1 1675 5.0 219...
  2. ... Ho Cho, Palanivel Rengasamy and Gary Sweeney Department of Biology, York University, Toronto, Canada Abstract Skeletal muscle insulin resistance is known to play an important role in the pathogenesis of diabetes, and one potential causative cellular mechanism is endoplasmic reticulum (ER) stress. Adiponectin...
  3. ...activation being a therapeutic target for atherosclerosis might be limited by the possibility of exacerbating insulin resistance. Journal of Molecular Endocrinology (2017) 58, 141–154 Correspondence should be addressed to F Zheng Email zhengfenpingjindi@hotmail. com Key Words f liver X receptor (LXR) f...
  4. ...have an increased prevalence of impaired glucose tolerance (IGT) and type 2 diabetes mellitus compared to women without PCOS in systematic reviews and meta-analyses, and they have an apparent increase in cardiovascular disease (Moran  et  al. 2010, de Groot  et  al. 2011). This highlights women...
  5. ...Key Words " adipocytes " autophagy " insulin resistance " progranulin " TNFR1 recently emerged as an important regulator of glucose sex- and BMI-matched insulin-sensitive counterparts ng that progranulin can be a nsulin sensitivity and energy ogranulin in adipose tissue in od, its link...
  6. ...10126 Turin, Italy 6Biophysics Laboratory, IGB – CNR, Via P. Castellino 111, 80131 Naples, Italy interfere with the canonical endocrine function that regulates metabolism in mature o BPA may be an important Key Words " bisphenol A " adipocytes " children " gene expression " metabolic homeostasis...
  7. ...activates protein kinase Cq and to M-H Zou Email [email protected] was associated with enhanced phosphorylation of PKCq, IKK, JNK, and IRS1 at serine 307 in Key Words " hypochlorous acid " insulin resistance " IRS1 " peroxynitrite d oxidative stress in adipose tion of inflammatory cells...
  8. ...enterochromaffin cells f calcium signaling DOI: 10.1530/JME-16-0063 http://.endocrinology-journals.org © 2016 Society for Endocrinology Printed in Great Britain Published by Bioscientifica Ltd. 202Research 57 3: b kalbe and others Ca2+ decrease and 5-HT release in QGP-1 cells release of serotonin after mechanical...
  9. ...-activated receptors, tumor necrotic factor-a, enhancer module is also located in the upstream region of the uridine diphosphate-5 0-glucuronosyltransferase DOI: 10.1530/JME-11-00461999, Seely & Solomon 2003, Kaaja & Greer 2005). However, the mechanism responsible for the insulin resistance during pregnancy...
  10. ..., to our Key Words " calcium signaling " fish " gene expression " hormone receptors Journal of Molecular Endocrinology (2015) 54, 305–314 Research J GU and others Stanniocalcin 1 binding and signaling in gill cells of Japanese eels 54 :3 305–314knowledge, the first to provide evidence of STC1 binding...
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