Searching journal content for aromatase (as phrase) in full text.

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  1. Review:
    • Marcel J M Schaaf
    Nuclear receptor research in zebrafish J Mol Endocrinol 59 (1) R65-R76, doi: 10.1530/JME-17-0031 first published on 24 April 2017
    ...aromatase b gene (cyp19a1b), resulting in specific GFP expression in radial glial cells in the area bordering the brain ventricles (Tong et al. 2009). Before 9 dpf, the GFP expression is only observed after induction by estrogens, enabling screening estrogenic activity of EDCs using exposure from 0 ~~~
  2. Research:
    • Li Zhang,
    • Jie Gao,
    • and Sheng Cui
    miR-21 is involved in norepinephrine-mediated rat granulosa cell apoptosis by targeting SMAD7 J Mol Endocrinol 58 (4) 199-210, doi: 10.1530/JME-16-0248
    ...aromatase (Xu  et  al. 2011). miR-224 is involved in TGF-β-induced granulosa cell proliferation and granulosa cell functions by targeting SMAD4 (Yao  et  al. 2010). MicroRNA-21 was shown to regulate granulosa cell apoptosis, and in vivo knockdown of miR-21 causes an increase in apoptosis (Carletti  ~~~
  3. Review:
    • T Traboulsi,
    • M El Ezzy,
    • J L Gleason,
    • and S Mader
    Antiestrogens: structure-activity relationships and use in breast cancer treatment J Mol Endocrinol 58 (1) R15-R31, doi: 10.1530/JME-16-0024 first published on 11 October 2016
    ...aromatase inhibitors) or estrogenic signaling (antiestrogens, AEs). AEs are steroids or steroid mimics that compete with endogenous estrogens (Fig.  1A) for binding to ERs and modify their activity as ligand-dependent transcriptional regulators (Hall et al. 2001, Ascenzi et al. 2006). However, some ~~~
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  4. Review:
    • Pilar Argente-Arizón,
    • Santiago Guerra-Cantera,
    • Luis Miguel Garcia-Segura,
    • Jesús Argente,
    • and Julie A Chowen
    Glial cells and energy balance J Mol Endocrinol 58 (1) R59-R71, doi: 10.1530/JME-16-0182 first published on 18 November 2016
    ...aromatase ~~~
  5. Research:
    • J J Allen,
    • S L Herrick,
    • and J E Fortune
    Regulation of steroidogenesis in fetal bovine ovaries: differential effects of LH and FSH J Mol Endocrinol 57 (4) 275-286, doi: 10.1530/JME-16-0152 first published on 3 October 2016
    ...aromatase (reviewed in Fortune & Quirk 1988). Immunohistochemical studies localized protein for aromatase in fetal bovine ovaries between 45 and 250 days of gestation (Burkhart et  al. 2010, Garverick et al. 2010), and gonadotropins are present in the serum of bovine fetuses of similar ages (Oxender ~~~
  6. Focused Review:
    • Rosalia C M Simmen and
    • Angela S Kelley
    Reversal of fortune: estrogen receptor-β in endometriosis J Mol Endocrinol 57 (2) F23-F27, doi: 10.1530/JME-16-0080 first published on 7 June 2016
    ...aromatase expression in baboon endometriotic lesions. Fertility and Sterility 80 (Supplement 2) 820–827. (doi:10.1016/S00150282(03)00982-8) Greaves E, Cousins FL, Murray A, Esnal-Zufiaurre A, Fassbender A, Horne AW & Saunders PT 2014 A novel mouse model of endometriosis mimics human phenotype and re ~~~
  7. Research:
    • Kesha Rana,
    • Maria W S Chiu,
    • Patricia K Russell,
    • Jarrod P Skinner,
    • Nicole K L Lee,
    • Barbara C Fam,
    • Jeffrey D Zajac,
    • and Helen E MacLean
    Muscle-specific androgen receptor deletion shows limited actions in myoblasts but not in myofibers in different muscles in vivo J Mol Endocrinol 57 (2) 125-138, doi: 10.1530/JME-15-0320 first published on 8 July 2016
    ...aromatase knockout mice (Hill et  al. 2007); therefore, it is possible that they are also regulated in an opposing manner by the AR in the CNS. In conclusion, our mouse models show that androgens acting through the DNA-binding actions of the AR do not play a major role in myoblasts or myofibers to r ~~~
  8. Focused Review:
    • Ylenia Perone and
    • Luca Magnani
    Going off the grid: ERα breast cancer beyond estradiol J Mol Endocrinol 57 (1) F1-F5, doi: 10.1530/JME-16-0062 first published on 5 May 2016
    ...aromatase inhibitors. Finally, we examine how the field is now considering the development of anticholesterol therapeutics and companion biomarkers to stratify and treat ERα breast cancer patients. In particular, we review recent progress in pharmaceutical strategies targeting the cholesterol molecu ~~~
  9. Focused Review:
    • Aurelie Nguyen Dinh Cat,
    • Malou Friederich-Persson,
    • Anna White,
    • and Rhian M Touyz
    Adipocytes, aldosterone and obesity-related hypertension J Mol Endocrinol 57 (1) F7-F21, doi: 10.1530/JME-16-0025
    ...aromatase inhibitor fadrozole be useful for clinical investigation of aldosteronesynthase inhibition? Journal of Hypertension 24 993–997. (doi:10.1097/01.hjh.0000226183.98439.b3) Morton NM, Paterson JM, Masuzaki H, Holmes MC, Staels B, Fievet C, Walker BR, Flier JS, Mullins JJ & Seckl JR 2004 Novel ~~~
  10. Review:
    • Hong Zhao,
    • Ling Zhou,
    • Anna Junjie Shangguan,
    • and Serdar E Bulun
    Aromatase expression and regulation in breast and endometrial cancer J Mol Endocrinol 57 (1) R19-R33, doi: 10.1530/JME-15-0310 first published on 11 April 2016
    ...aromatase and estrogen in the normal breast and in the development of breast cancers. Aromatase, the key enzyme for estrogen production, is comprised of at least ten partially tissue-selective and alternatively used promoters. These promoters are regulated by distinct signaling pathways to control a ~~~
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