Epigenetic programming of the neuroendocrine stress response by adult life stress

  1. M J A G Henckens2
  1. 1Department of Anatomy, Donders Institute for Brain, Cognition, and Behaviour, Radboud University Medical Centre, Nijmegen, The Netherlands
  2. 2Department of Cognitive Neuroscience, Donders Institute for Brain, Cognition, and Behaviour, Radboud University Medical Centre, Nijmegen, The Netherlands
  1. Correspondence should be addressed to B C J Dirven; Email: bart.dirven{at}radboudumc.nl
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    Figure 1

    Animal models of stress. (A) Stressed vs control contrast: half of the animals from a genetically homogeneous group undergoes a certain stress procedure, while the other half receives a sham procedure. (B) Vulnerable vs resilient contrast: all animals from a group undergo the same stress procedure and are tested on stress-related symptomatology afterwards. The behaviourally most resilient animals are compared to the behaviourally most vulnerable animals.

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  1. doi: 10.1530/JME-17-0019 J Mol Endocrinol 59 R11-R31
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