Mechanisms of tamoxifen resistance

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   Figure 1

   The genomic (classical and non-classical) and non-genomic actions of the ER
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   Figure 2

   The cellular kinase pathways interacting with ER function (with thanks to Dr Lesley-Ann Martin)
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   Figure 3

   Clinical responses according to EGFR/HER2 status in patients treated with neoadjuvant endocrine therapy.

• © 2004 Society for Endocrinology