Searching journal content for high-fat diet (as phrase) in full text.

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  1. Research:
    • Penny Ahlstrom,
    • Esther Rai,
    • Suharto Chakma,
    • Hee Ho Cho,
    • Palanivel Rengasamy,
    • and Gary Sweeney
    Adiponectin improves insulin sensitivity via activation of autophagic flux J Mol Endocrinol 59 (4) 339-350, doi: 10.1530/JME-17-0096
    ...leading to insulin resistance. For example, inflammation or high-fat diet can lead to ER stress (Dai etal. 2016, Kwak etal. 2016, Liong & Lappas 2016). Various reports have demonstrated that treatments which alleviate skeletal muscle ER stress induced by stressors such as highfat diet or palmitate ~~~
  2. Research:
    • Susan M van den Berg,
    • Andrea D van Dam,
    • Pascal J H Kusters,
    • Linda Beckers,
    • Myrthe den Toom,
    • Saskia van der Velden,
    • Jan Van den Bossche,
    • Irma van Die,
    • Mariëtte R Boon,
    • Patrick C N Rensen,
    • Esther Lutgens,
    • and Menno P J de Winther
    Helminth antigens counteract a rapid high-fat diet-induced decrease in adipose tissue eosinophils J Mol Endocrinol 59 (3) 245-255, doi: 10.1530/JME-17-0112 first published on 10 July 2017
    ..., with a prominent role for eosinophils and interleukin (IL)-4-induced anti-inflammatory macrophages. We determined eosinophil numbers in epididymal WAT (EpAT), subcutaneous WAT (ScAT) and BAT after 1day, 3days or 1week of high-fat diet (HFD) feeding in C57Bl/6 mice. One day of HFD resulted in a rapid drop ~~~
  3. Research:
    • Yajie Guo,
    • Junjie Yu,
    • Chunxia Wang,
    • Kai Li,
    • Bin Liu,
    • Ying Du,
    • Fei Xiao,
    • Shanghai Chen,
    • and Feifan Guo
    miR-212-5p suppresses lipid accumulation by targeting FAS and SCD1 J Mol Endocrinol 59 (3) 205-217, doi: 10.1530/JME-16-0179 first published on 30 June 2017
    ...potential therapeutic approaches to NAFLD. In summary, our study showed that leucine deprivation induces the expression of miR-212-5p in a GCN2/ATF4-dependent manner. miR-212-5p suppresses lipid accumulation in liver by targeting FAS and SCD1 under both normal diet and high-fat diet conditions ~~~
  4. Research:
    • Yu-Guang Ma,
    • Liang Liang,
    • Yin-Bin Zhang,
    • Bao-Feng Wang,
    • Yun-Gang Bai,
    • Zhi-Jun Dai,
    • Man-Jiang Xie,
    • and Zhong-Wei Wang
    Berberine reduced blood pressure and improved vasodilation in diabetic rats J Mol Endocrinol 59 (3) 191-204, doi: 10.1530/JME-17-0014 first published on 17 May 2017
    ...SpragueDawley rats (~190 g) were purchased from Medical Laboratory Animal Center of Xian Jiaotong University. According to our previous description (Maetal. 2016), a high-fat diet plus low-dose injections of streptozotocin (STZ) were used to establish the diabetic rat. The high-fat diet consisted ~~~
  5. Research:
    • Haoyong Yu,
    • Mingliang Zhang,
    • Yunqin Ma,
    • Junxi Lu,
    • Jiemin Pan,
    • Pan Pan,
    • Haibing Chen,
    • and Weiping Jia
    5-ALA ameliorates hepatic steatosis through AMPK signaling pathway J Mol Endocrinol 59 (2) 121-128, doi: 10.1530/JME-16-0260 first published on 31 May 2017
    ...therapeutic effects on NAFLD and elucidate the signal pathway mediating these effects. To explore these questions, we fed C57BL/6J mice a high-fat diet (HFD) to induce a fatty liver disease and supplemented the diet-induced obese (DIO) mice with 5-ALA. The mice in the presence of 5-ALA demonstrated a decrease ~~~
  6. Research:
    • Long The Nguyen,
    • Sonia Saad,
    • Yi Tan,
    • Carol Pollock,
    • and Hui Chen
    Maternal high-fat diet induces metabolic stress response disorders in offspring hypothalamus J Mol Endocrinol 59 (1) 81-92, doi: 10.1530/JME-17-0056 first published on 12 May 2017
    ...play important roles in such transgenerational effect. In this study, we show that offspring born to high-fat diet-fed dams showed significantly increased body weight and glucose intolerance, adiposity and plasma triglyceride level at weaning. Hypothalamic mRNA level of the orexigenic neuropeptide Y ~~~
  7. Review:
    • Marcel J M Schaaf
    Nuclear receptor research in zebrafish J Mol Endocrinol 59 (1) R65-R76, doi: 10.1530/JME-17-0031 first published on 24 April 2017
    ..., a standard assay has been developed for chemical screening of potential drugs or toxic compounds (Jonesetal. 2008, TingaudSequeira et al. 2011). In this zebrafish obesogenic test (ZOT), larvae are fed a standard or high-fat diet for one day, and are subsequently starved for two days with chemical ~~~
  8. Research:
    • Ting Qi,
    • Yanming Chen,
    • Honggui Li,
    • Ya Pei,
    • Shih-Lung Woo,
    • Xin Guo,
    • Jiajia Zhao,
    • Xiaoxian Qian,
    • Joseph Awika,
    • Yuqing Huo,
    • and Chaodong Wu
    A role for PFKFB3/iPFK2 in metformin suppression of adipocyte inflammatory responses J Mol Endocrinol 59 (1) 49-59, doi: 10.1530/JME-17-0066
    ..., there are studies in which metformin does not alter body weight and/or adipose tissue inflammation, in particular in rodents fed with an high-fat diet (HFD) (Anthonyetal. 2013, Shinetal. 2013, Songetal. 2001, Wooetal. 2014). Given this discrepancy, there is a need to gain mechanistic insights of whether ~~~
  9. Review:
    • J Jason Collier,
    • Tim E Sparer,
    • Michael D Karlstad,
    • and Susan J Burke
    Pancreatic islet inflammation: an emerging role for chemokines J Mol Endocrinol 59 (1) R33-R46, doi: 10.1530/JME-17-0042 first published on 18 April 2017
    ...high-fat diet through secreted elastase. Nature Medicine 18 1407–1412. (doi:10.1038/nm.2885) Thompson BD, Jin Y, Wu KH, Colvin RA, Luster AD, Birnbaumer L & Wu MX 2007 Inhibition of G alpha i2 activation by G alpha i3 in CXCR3-mediated signaling. Journal of Biological Chemistry 282 9547–9555. (doi:1 ~~~
  10. Review:
    • Ahmed A Hasan and
    • Berthold Hocher
    Role of soluble and membrane-bound dipeptidyl peptidase-4 in diabetic nephropathy J Mol Endocrinol 59 (1) R1-R10, doi: 10.1530/JME-17-0005 first published on 18 April 2017
    ...expression was identified at the brush border membrane of human proximal tubular cells (Stangeetal. 1996). Moreover, induction of diabetes, using streptozotocin plus high fat diet, up-regulated DPP-4 expression in the rat kidneys, primarily in renal tubular cells (Yangetal. 2007). In addition, our group ~~~
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