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  1. ...a delay in the acquisition of phagocytic capacity by macrophages, though the inflammation resolves at a similar time to that in control mice (Gilmour et al. 2006). Reduced cholesterol accumulation in macrophages plays a role in the atheroprotective and anti-inflammatory effects of global 11-HSD1 ~~~
  2. ...determined from calculations as described previously (Gault et al. 2015). Lipids (total cholesterol CH200; and triglycerides TR210) and ALT (AL1205) were measured using enzymatic kits from Randox Laboratories (Crumlin, UK). Plasma corticosterone (ab100712) and IL-6 (ab108821) were measured using ~~~
  3. ...described elsewhere to optimize the assay for mouse serum (Weissetal. 1998). The detection limits were 1 g/dL and 0.02 g/dL for total T4 and total T3, respectively. Serum triglycerides (TG) and total cholesterol (TC) were also determined using commercial kits (Wako Pure Chemical Industries). Next ~~~
  4.; oral Kersseboometal. (2014), Zadaetal. (2016) Zebrafish, hypo Purkinje cell development Mice, hypo 200 g/kg/day; 12day; oral Kersseboometal. (2014), Delbaereetal. (2017) Chicken, hypo Liver Cholesterol = Rats, eu 200 g/kg/day; 4week; oral Autissieretal. (1980) Biliary cholesterol ~~~
  5. .... Thyroid-stimulating hormone (TSH) levels remain unaffected, while plasma cholesterol concentrations were lower in HS than PF animals. Hepatic marker genes for TH action (THRA, DIO1 and PPARGC1) decreased after HS and were lower compared to PF cows but only post-partum. Proteomics data revealed reduced ~~~
  6. ..., as treatments for placental dysfunction. This review: (1) highlights potential candidate drug targets in the placenta effectors of improved uteroplacental blood flow, anti-oxidants, heme oxygenase induction, inhibition of HIF, induction of cholesterol synthesis pathways, increasing insulinlike growth factor ~~~
  7. ...and others 2017 Society for Endocrinology Printed in Great Britain Published by Bioscientifica Ltd. 234:1 crucial steps of steroid synthesis: cholesterol side-chain cleavage enzyme, a mitochondrial enzyme commonly referred to as P450scc (Cyp11a1) that catalyzes ~~~
  8. ...glucose metabolism. In this study, the metabolic syndrome-like phenotype was characterized and mechanisms of impaired hepatic fatty acid, cholesterol and glucose metabolism in pre-obese (2-month-old) and obese (47-month-old) OE-NPYDBH mice were elucidated. Susceptibility to T2D was assessed by subjecting ~~~
  9. ...acids, total cholesterol and triacylglycerol) after a dietary challenge (Cansby et al. 2013, Amrutkar et al. 2015b). Moreover, fasting blood glucose levels are similar in Stk25 transgenic and wild-type mice on a high-fat diet and in age-matched lean chow-fed controls (Cansbyetal. 2013). Therefore ~~~
  10. ...for Endocrinology Printed in Great Britain Published by Bioscientifica Ltd. 234:1 plasma cortisol was associated with higher plasma renin, lower serum high-density lipoprotein cholesterol and higher waist circumference but not with blood pressure, carotid intima-media thickness or echocardiographic parameters ~~~
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