Searching journal content for neuroendocrine (as phrase) in full text.

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  1. ...neuroendocrine cancers and adrenocortical cancers. It is evident from their review that across the different tumor subtypes, there is tremendous variability in efficacy in using checkpoint inhibitors. This is in part because we are as yet unable to predict and define the tumor-specific (and context- ~~~
  2. ...neuroendocrine tumors. We present the challenges and the opportunities of using immune checkpoint inhibitors against these endocrine malignancies, highlighting the breakthroughs and pitfalls that have recently emerged. Introduction Immune checkpoint inhibitors are agents that act by inhibiting immun ~~~
  3. ...neuroendocrine cancer. Clinical Cancer Research 14 4298–4305. (doi:10.1158/1078-0432.CCR-08-0587) Pardoll DM 2012 The blockade of immune checkpoints in cancer immunotherapy. Nature Reviews Cancer 12 252–264. (doi:10.1038/ nrc3239) Parhar RS, Zou M, Al-Mohanna FA, Baitei EY, Assiri AM, Meyer BF & Shi ~~~
  4. ...neuroendocrine NCT02628067 Prembrolizumab II; not yet recruiting Anti-PD1 Thyroid, neuroendocrine NCT03012620 Prembrolizumab I; recruiting Anti-PD1 Thyroid, pancreatic Enoblituzumab (MGA271) NCT02475213 Prembrolizumab II; not yet recruiting Anti-PD1 Thyroid Lenvatinib NCT02973997 Prembrolizumab II; ~~~
  5. ...neuroendocrine 7 tumour syndromes, MEN type 2A (MEN2A) and MEN type 2B (MEN2B). They are typified by the 8 development of medullary thyroid carcinoma (MTC), phaeochromocytoma and parathyroid 9 hyperplasia in MEN2A, and MTC, phaeochromocytomas, ganglioneuromatosis and skeletal 10 abnormalities in MEN ~~~
  6. ...neuroendocrine 1 neoplasms: more flaws than fame 2 3 Vincenzo Marotta , Maria Chiara Zatelli , Concetta Sciammarella , Maria Rosaria Ambrosio , 4 Marta Bondanelli , Annamaria Colao , Antongiulio Faggiano 5 1. Department of Clinical Medicine and Surgery, Federico II University, Naples, Italy 6 2. Sec ~~~
  7. ...neuroendocrine cell-specific phenotype and loss of AR, of which treatment option is limited 73 and results in high mortality. Accumulating evidences suggest that prostate cancer 74 stem/progenitor-like cells (PCSCs; also called prostate cancer stem cells, tumor initiating or 75 progenitor cells) may ~~~
  8. ...neuroendocrine tumors derived from 46 neural-crest cells of the sympathetic and parasympathetic nervous system - PCs arising in the adrenal 47 medulla and PGLs in paraganglia outside the adrenal medulla. Although rare, they often occur as part 48 of hereditary endocrine tumor syndromes and their stu ~~~
  9. ...neuroendocrine neoplasia originating 41 from the C cell component of the thyroid gland. MTC accounts for about 5% of all 42 thyroid malignant tumors and can occur either as sporadic (about 75% of cases) or 43 familial (about 25% of cases) form. Hereditary MTC occurs in the context of different 44 au ~~~
  10. ...neuroendocrine neoplasms, breast and soft tissue tumors) beyond the parathyroid adenoma, gastrinoma and prolactinoma described originally, and also to understand the genetic, epigenetic and post-translational mechanisms behind this disorder. 20th anniversary of the MEN1 gene cloning Researchers arou ~~~
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