Searching journal content for estrogen receptor (as phrase) in full text.

Displaying results 1-10 of 581
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  1. Research:
    • Zhu Wang,
    • Dinglan Wu,
    • Chi-Fai Ng,
    • Jeremy Yuen-Chun Teoh,
    • Shan Yu,
    • Yuliang Wang,
    • and Franky Leung Chan
    Nuclear receptor profiling in prostatospheroids and castration-resistant prostate cancer Endocr Relat Cancer ERC-17-0280, doi:10.1530/ERC-17-0280 first published on 17 October 2017
    ...1866-1870. 470 Cheung CP, Yu S, Wong KB, Chan LW, Lai FM, Wang X, Suetsugi M, Chen S & Chan FL 471 2005 Expression and functional study of estrogen receptor-related receptors in human 472 prostatic cells and tissues. J Clin Endocrinol Metab 90 1830-1844. 473 Page 20 of 38 21 Grasso CS, Wu YM, Robinson ~~~
  2. Review:
    • Gido Snaterse,
    • Jenny A Visser,
    • Wiebke Arlt,
    • and Johannes Hofland
    Circulating steroid hormone variations throughout different stages of prostate cancer Endocr Relat Cancer 24 (11) R403-R420, doi:10.1530/ERC-17-0155 first published on 18 September 2017
    ...estradiol (E2) has risen in recent years, especially as a possible factor in the development of prostate cancer. A shift from apoptosis-inducing estrogen receptor (ER)- signaling to the growth-stimulatory effects of ER- during PC evolution suggests a proliferative role of estrogens in advanced disease ~~~
  3. Commentary:
    • Giorgio Secreto,
    • Paola Muti,
    • Milena Sant,
    • Elisabetta Meneghini,
    • and Vittorio Krogh
    Medical ovariectomy in menopausal breast cancer patients with high testosterone levels: a further step toward tailored therapy Endocr Relat Cancer 24 (11) C21-C29, doi:10.1530/ERC-17-0251 first published on 16 August 2017
    ..., Milano, Italy Abstract Five years of adjuvant therapy with anti-estrogens reduce the incidence of disease progression by about 50% in estrogen receptor-positive breast cancer patients, but late relapse can still occur after anti-estrogens have been discontinued. In these patients, excessive androgen ~~~
  4. Review:
    • Iuri Martin Goemann,
    • Mirian Romitti,
    • Erika L Souza Meyer,
    • Simone Magagnin Wajner,
    • and Ana Luiza Maia
    Role of thyroid hormones in the neoplastic process: an overview Endocr Relat Cancer 24 (11) R367-R385, doi:10.1530/ERC-17-0192
    ...the estrogen receptor alpha (ER). This observation highlights the crosstalk between THs and estrogen signaling pathways in certain cancer cells, culminating in specific intranuclear events Figure2 Proposed mechanism of genomic and nongenomic actions of THs in the neoplastic process. The actions of THs occur ~~~
  5. Thematic Review:
    • Sunita K Agarwal
    The future: genetics advances in MEN1 therapeutic approaches and management strategies Endocr Relat Cancer 24 (10) T119-T134, doi:10.1530/ERC-17-0199
    ...estrogen receptor activation to histone H3K4 trimethylation. Cancer Research 66 4929–4935. (doi:10.1158/0008-5472.CAN-05-4461) Dreijerink KM, Varier RA, van Nuland R, Broekhuizen R, Valk GD, van der Wal JE, Lips CJ, Kummer JA & Timmers HT 2009 Regulation of vitamin D receptor function in MEN1-relate ~~~
  6. Thematic Review:
    • Hermine Mohr and
    • Natalia S Pellegata
    Animal models of MEN1 Endocr Relat Cancer 24 (10) T161-T177, doi:10.1530/ERC-17-0249 first published on 25 July 2017
    ...and inducible mouse models were generated. Schnepp and coworkers (Schnepp et al. 2006) crossed the Men138flox/flox/Rip-Cre mice described above (Crabtree etal. 2003) with Cre-ER (estrogen receptor) transgenic mice expressing Cre under the control of a ubiquitously active human ubiquitin carrier 9 (UBC9 ~~~
  7. Thematic Review:
    • Koen M A Dreijerink,
    • H T Marc Timmers,
    • and Myles Brown
    Twenty years of menin: emerging opportunities for restoration of transcriptional regulation in MEN1 Endocr Relat Cancer 24 (10) T135-T145, doi:10.1530/ERC-17-0281 first published on 15 August 2017
    ...is able to interact with the estrogen receptor alpha (ER) ligandbinding domain in an estradiol (E2)-dependent fashion (Dreijerinketal. 2006). This interaction is important for transcription of ER target genes through recruitment of H3K4me3 methyltransferase activity. Menin also regulates transcription ~~~
  8. Thematic Review:
    • Rachel S van Leeuwaarde,
    • Joanne M de Laat,
    • Carolina R C Pieterman,
    • Koen Dreijerink,
    • Menno R Vriens,
    • and Gerlof D Valk
    The future: medical advances in MEN1 therapeutic approaches and management strategies Endocr Relat Cancer 24 (10) T179-T193, doi:10.1530/ERC-17-0225 first published on 2 August 2017
    ...(Seigne et al. 2013). However, in sporadic breast cancer, menin seems to have a proliferative function. In breast cancer cell lines, menin is a co-activator of the estrogen receptor alpha, a critical driver in approximately 70% of sporadic breast cancer cases. Menin has been reported to be involved ~~~
  9. Review:
    • Catherine Zabkiewicz,
    • Jeyna Resaul,
    • Rachel Hargest,
    • Wen Guo Jiang,
    • and Lin Ye
    Bone morphogenetic proteins, breast cancer, and bone metastases: striking the right balance Endocr Relat Cancer 24 (10) R349-R366, doi:10.1530/ERC-17-0139 first published on 21 July 2017
    ...the bony metastatic niche. The selective estrogen receptor modulator raloxifene increased the activity of the BMP-4 promoter in U-2 OS osteoblast-like cells. ER- is thought to be indispensable for this effect on the BMP-4 promoter and may be part of the mechanism of this agents in reducing both ~~~
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  10. Review:
    • Melissa Gamat and
    • Douglas G McNeel
    Androgen deprivation and immunotherapy for the treatment of prostate cancer Endocr Relat Cancer ERC-17-0145, doi:10.1530/ERC-17-0145 first published on 16 August 2017
    ...testosterone to be aromatized to estrogen, which may 212 also have effects on the immune system. Using steroid binding assays, human CD8+ T cells were 213 determined to express estrogen receptors (Stimson 1988), and subsequent studies using flow cytometry 214 and immunofluorescence identified both ER and ER ~~~
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