Searching journal content for TERT promoter mutations (as phrase) in full text.

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  1. ...TERT promoter mutations occur rarely in PC/PGL, we 35 hypothesized that other mechanisms - such as structural variations - may underlie TERT activation in 36 these tumors. From 35 PC and four PGL, we identified three primary PC that developed metastases 37 with elevated TERT expression, each of whic ~~~
  2. ...TERT promoter mutations cooperatively identify the most aggressive papillary thyroid cancer with highest recurrence. Journal of Clinical Oncology 32 2718–2726. (doi:10.1200/JCO.2014.55.5094) Xing M, Liu R, Liu X, Murugan AK, Zhu G, Zeiger MA, Pai S & Bishop J 2015 Association between BRAF V600E muta ~~~
  3. ...TERT promoter mutations occur frequently in gliomas and a subset of tumors derived from cells with low rates of self-renewal. PNAS 110 6021–6026. (doi:10.1073/pnas.1303607110) Kim DH, Nagano Y, Choi IS, White JA, Yao JC & Rashid A 2008 Allelic alterations in well-differentiated neuroendocrine tumors ~~~
  4. ...TERT promoter mutations and validation of mutations Mutations in the BRAF gene were validated using a standard PCR and primers designed for exon 15 as previously reported (Davidsson  et  al. 2008): BRAFEx15 For: TGCTTGCTCTGATAGGAAAATGAG and BRAFEx15 Rev: TCTCAGGGCCAAAAATTTAATCA. Mutations in the pro ~~~
  5. ...TERT promoter mutations have been observed in thyroid carcinomas with aggressive biological behaviours. It is associated with tumour size, advanced stage, extrathyroidal invasion, lymph node metastases, distant metastases, BRAF mutation positivity, cancer recurrence and poor prognosis of patients wi ~~~
  6. ...TERT promoter mutations were detected in 49 (12.0%) of 407 tested cases: 11.1% (n = 45) TERT C228T and 1.0% (n = 4) C250T mutations. TERT promoter mutations were detected in 9.8% (32 of 326) of papillary thyroid carcinomas, 16.7% (11 of 66) of follicular thyroid carcinomas, 33.3% (2 of 6) of poorly ~~~
  7. ...TERT promoter mutations in papillary thyroid microcarcinomas. Thyroid 25 1013–1019. (doi:10.1089/thy.2015.0101) Essig GF Jr, Porter K, Schneider D, Debora A, Lindsey SC, Busonero G, Fineberg D, Fruci B, Boelaert K, Smit JW, et al. 2013 Fine needle aspiration and medullary thyroid carcinoma: the risk ~~~
  8. ...TERT promoter mutations in familial and sporadic melanoma. Science 339 959–961. (doi:10.1126/science.1230062) Kakudo K, Bai Y, Liu Z, Li Y, Ito Y & Ozaki T 2012 Classification of thyroid follicular cell tumors: with special reference to borderline lesions. Endocrine Journal 59 1–12. (doi:10.1507/end ~~~
  9. ...TERT promoter mutations in papillary thyroid cancer (PTC) has been recently established, but the role of RAS mutation in this genetic interplay remains to be established. Using The Cancer Genome Atlas (TCGA) data of patients with PTC from 19 medical centers, we investigated the interactions among th ~~~
  10. ...TERT promoter mutations in tumour progression (BornsteinQuevedo et al. 2003). Starting from the study by Liu and coworkers (2013), who firstly reported the mutations in follicular cell-derived thyroid cancers, a relevant body of research has been performed by 3 leading groups and by the TCGA, focusi ~~~
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