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Increased nuclear beta catenin in Shb knockout islet. Islets were stained for beta catenin (green) and DAPI (blue), the latter to visualize nuclei. Original magnification 200x. Credit: Ida Alenkvist, Oleg Dyachok, Geng Tian, Jia Li, Saba Mehrabanfar, Yang Jin, Bryndis Birnir, Anders Tengholm and Michael Welsh, Uppsala Universiy, Sweden